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Breast cancer is lowkey the most common female cancer, and estrogen and progesterone receptors are the main goons behind tumor growth. With drugs like tamoxifen, survival rates have gone sigma high for those with hormone receptor-positive cancers. The edge is knowing that for receptors to be considered positive, at least 1% of cells need to stain positive. Quality assurance in testing is dank for managing treatments. Even with genomic tests popping up, hormone receptor status is still the OG biomarker for predicting outcomes. This history is crucial as we navigate the future of breast cancer therapy.