Microglia Repopulation in Mice

Skibidi vibes in the lab as researchers dive into the dank world of microglia, the brain's goon squad. They are lowkey essential for keeping the central nervous system chill but can edge into chaos during inflammation. Using some sigma-level techniques like scRNA-seq and confocal imaging, the team tracked how these cells bounce back after a CSF1R inhibitor sends them packing. Turns out, they repopulate fast, but their new form is not all good news, with increased inflammatory genes popping up, especially in older mice. This study ships us closer to understanding MG's role in brain health.