Vancomycin Dosing in Hemodialysis

Skibidi, let us dive into the dank world of vancomycin and hemodialysis. To hit that sigma edge, remember the three key equations for loading dose: LD equals volume of distribution times actual body weight times change in concentration. For dialysis goons, the parameters shift, so the volume is 0.92 L/kg. Lowkey, you need to keep track of that elimination rate constant, which is 0.0064 hr -1 when not on dialysis. For normal infections, aim for a loading dose of 25 mg/kg, but if you are dealing with something special, adjust that Δ [C] higher. Stay sharp and ship it right!